Psychedelic Compound (DMT) for Treatment-Resistant Depression
Recruitment Closed
Psychedelic Compound (DMT) for Treatment-Resistant Depression
If standard antidepressants haven’t worked for you, you’re not alone. Many people with Treatment-Resistant Depression struggle to find an effective option. atai Therapeutics Inc. is researching an investigational treatment that includes DMT, a psychedelic compound, combined with psychological support.
This study is designed for individuals with major depression who have not responded to traditional antidepressant treatments. By participating, you may gain access to a potential new approach under the care of experienced clinical researchers.
You may be eligible if you:
- Are 18 to 65 years of age
- Have been diagnosed with major depression (single or recurrent episodes)
- Have not responded to 2–5 antidepressant treatments for your current episode
- Meet additional study criteria
What to Expect:
- The study lasts five months
- Participation involves a combination of remote and in-clinic visits, including three dosing days.
- Study clinicians will provide medical support to help taper off certain medications, including current antidepressants
- Reimbursement may be available for travel and other study-related expenses
Learn More:
If you’d like to see if this study is right for you, check your eligibility in the link below.
Site Principal Investigator (Study Doctor):

