Psychedelic Compound (DMT) for Treatment-Resistant Depression

Recruitment Closed

Psychedelic Compound (DMT) for Treatment-Resistant Depression

If standard antidepressants haven’t worked for you, you’re not alone. Many people with Treatment-Resistant Depression struggle to find an effective option. atai Therapeutics Inc. is researching an investigational treatment that includes DMT, a psychedelic compound, combined with psychological support.

This study is designed for individuals with major depression who have not responded to traditional antidepressant treatments. By participating, you may gain access to a potential new approach under the care of experienced clinical researchers.

You may be eligible if you:

  • Are 18 to 65 years of age
  • Have been diagnosed with major depression (single or recurrent episodes)
  • Have not responded to 2–5 antidepressant treatments for your current episode
  • Meet additional study criteria

What to Expect:

  • The study lasts five months
  • Participation involves a combination of remote and in-clinic visits, including three dosing days.
  • Study clinicians will provide medical support to help taper off certain medications, including current antidepressants
  • Reimbursement may be available for travel and other study-related expenses

Learn More:

If you’d like to see if this study is right for you, check your eligibility in the link below. 

Site Principal Investigator (Study Doctor):

Dr. Shimi Kang, MD, FRCPC